https://socictopen.socict.org/files/original/6ee1813d284383990f2d971aec0b1645.pdf feea7fb602f1f264c90b93e52ee32c5d Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Household exposure to SARS-CoV-2 and association with COVID-19 severity: a Danish nationwide cohort study. Creator An entity primarily responsible for making the resource Marcella M Broccia, Victoria Elizabeth V E de Knegt, Elisabeth Helen Anna E H A Mills, Amalie Lykkemark A L Møller, Filip F Gnesin, Thea K T K Fischer, Nertila N Zylyftari, Stig Nikolaj S N Blomberg, Mikkel Porsborg M P Andersen, Morten M Schou, Emil E Fosbøl, Kristian K Kragholm, Helle Collatz H C Christensen, Laura Bech L B Polcwiartek, Matthew M Phelps, Lars L Køber, Christian C Torp-Pedersen Description An account of the resource Households are high-risk settings for the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Severity of Coronavirus disease 2019 (COVID-19) is likely associated with the infectious dose of SARS-CoV-2 exposure. We therefore aimed to assess the association between SARS-CoV-2 exposure within households and COVID-19 severity. We performed a Danish nationwide register-based cohort study including laboratory-confirmed SARS-CoV-2 infected individuals from 22 February to 6 October 2020. Household exposure to SARS-CoV-2 was defined as having one individual tested positive for SARS-CoV-2 within the household. Cox proportional-hazards models were used to estimate the association between 'critical COVID-19' within and between households with and without secondary cases. From 15,063 multi-person households, 19,773 SARS-CoV-2 positive individuals were included; 11,632 were categorized as index cases without any secondary household cases, 3,431 as index cases with secondary cases, i.e. 22.8% of multi-person households, and 4,710 as secondary cases. 'Critical COVID-19' occurred in 2.9 % of index cases living with no secondary cases, 4.9 % of index cases with secondary cases, and 1.3 % of secondary cases. The adjusted hazard ratio for 'critical COVID-19' among index cases versus secondary cases within the same household was 2.50 (95%CI=1.88-3.34), 2.27 (95%CI=1.77-2.93) for index cases in households with no secondary cases versus secondary cases, and 1.1 (95%CI=0.93-1.30) for index cases with secondary cases versus index cases without secondary cases. We found no increased hazard ratio of 'critical COVID-19' among household members of infected SARS-CoV-2 index cases. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource transmission, viral load, corona, Death, infectious dose Identifier An unambiguous reference to the resource within a given context 10.1093/cid/ciab340 Source A related resource from which the described resource is derived Clinical infectious diseases : an official publication of the Infectious Diseases Society of America