https://socictopen.socict.org/files/original/35858f34a602b10be0ea06c87ee5bbfa.pdf 19242e0fcfeb577efc68fc908b9e914b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Elucidating the Neuropathologic Mechanisms of SARS-CoV-2 Infection Creator An entity primarily responsible for making the resource Charles R. Harrington, Mar Pacheco-Herrero, Luis O. Soto-Rojas, Yazmin M. Flores-Martinez, Marcos M. Villegas-Rojas, Alfredo M. León-Aguilar, Paola A. Martínez-Gómez, B. Berenice Campa-Córdoba, B. Berenice Campa-Córdoba, Ricardo Apátiga-Pérez, Ricardo Apátiga-Pérez, Carolin N. Corniel-Taveras, Jesabelle de J. Dominguez-García, Víctor Manuel Blanco-Alvarez, José Luna-Muñoz, José Luna-Muñoz Description An account of the resource The current pandemic caused by the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a public health emergency. To date, March 1, 2021, coronavirus disease 2019 (COVID-19) has caused about 114 million accumulated cases and 2.53 million deaths worldwide. Previous pieces of evidence suggest that SARS-CoV-2 may affect the central nervous system (CNS) and cause neurological symptoms in COVID-19 patients. It is also known that angiotensin-converting enzyme-2 (ACE2), the primary receptor for SARS-CoV-2 infection, is expressed in different brain areas and cell types. Thus, it is hypothesized that infection by this virus could generate or exacerbate neuropathological alterations. However, the molecular mechanisms that link COVID-19 disease and nerve damage are unclear. In this review, we describe the routes of SARS-CoV-2 invasion into the central nervous system. We also analyze the neuropathologic mechanisms underlying this viral infection, and their potential relationship with the neurological manifestations described in patients with COVID-19, and the appearance or exacerbation of some neurodegenerative diseases. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource SARS-CoV-2, Neuroinflammation, neurodegenerative diseases, blood-brain barrier, neurological alterations, storm cytokine syndrome Identifier An unambiguous reference to the resource within a given context 10.3389/fneur.2021.660087 Source A related resource from which the described resource is derived Epidemiology and Health Publisher An entity responsible for making the resource available Korean Society of Epidemiology Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Neurology. Diseases of the nervous system