https://socictopen.socict.org/files/original/d12ffde9a8bbdb80f517df1a8d7a7480.pdf 3075be4748c3b627fb178fc227e21f6b Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Potential Effects of Melatonin and Micronutrients on Mitochondrial Dysfunction during a Cytokine Storm Typical of Oxidative/Inflammatory Diseases. Creator An entity primarily responsible for making the resource Vicente Lahera, Russel J Reiter, Virna Margarita Martín Giménez, Walter Manucha, Natalia de Las Heras, León Ferder Description An account of the resource Exaggerated oxidative stress and hyper-inflammation are essential features of oxidative/inflammatory diseases. Simultaneously, both processes may be the cause or consequence of mitochondrial dysfunction, thus establishing a vicious cycle among these three factors. However, several natural substances, including melatonin and micronutrients, may prevent or attenuate mitochondrial damage and may preserve an optimal state of health by managing the general oxidative and inflammatory status. This review aims to describe the crucial role of mitochondria in the development and progression of multiple diseases as well as the close relationship among mitochondrial dysfunction, oxidative stress, and cytokine storm. Likewise, it attempts to summarize the main findings related to the powerful effects of melatonin and some micronutrients (vitamins and minerals), which may be useful (alone or in combination) as therapeutic agents in the treatment of several examples of oxidative/inflammatory pathologies, including sepsis, as well as cardiovascular, renal, neurodegenerative, and metabolic disorders. Date A point or period of time associated with an event in the lifecycle of the resource 2021 Subject The topic of the resource covid-19, cytokine storm, melatonin, Micronutrients, Minerals, vitamins, mitochondrial dysfunction, oxidative-inflammatory disorders Identifier An unambiguous reference to the resource within a given context 10.3390/diseases9020030 Source A related resource from which the described resource is derived Diseases (Basel, Switzerland)