https://socictopen.socict.org/files/original/f2c1cb0553adcc3563bb95ad6a305493.pdf 69d1c6245d908ffaae2cc9081c913fbe Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Coronavirus Description An account of the resource Dominio científico: Coronavirus Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Nasopharyngeal isolates and their clinical impact on young children with asthma: a pilot study Creator An entity primarily responsible for making the resource Alsuwaidi AR, Alkalbani AM, Alblooshi A, George J, Albadi G, Kamal SM, Narchi H, Souid AK Description An account of the resource Ahmed R Alsuwaidi,1 Alia M Alkalbani,2 Afaf Alblooshi,1 Junu George,1 Ghaya Albadi,1 Salwa M Kamal,3 Hassib Narchi,1 Abdul-Kader Souid1 1Department of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates; 2Tawam Hospital, Abu Dhabi Health Services Company (SEHA), Al Ain, United Arab Emirates; 3Ambulatory Healthcare Services, SEHA, Abu Dhabi, United Arab Emirates Introduction: Respiratory infections have significant effects on childhood asthma. Viral respiratory infections, such as rhinovirus and respiratory syncytial virus are likely to be important in the development and exacerbation of asthma. In this study, we investigated the nasopharyngeal colonization in children with asthma to determine the prevalence of pathogens and their contribution to respiratory symptoms and airway resistance during winter. Methods: From December 2016 to March 2017, 50 nasopharyngeal specimens were collected from 18 patients (age, 5.0±1.1 years) with asthma and 9 specimens from 9 control children (age, 4.9±1.0 years). Samples were tested for 19 viruses and 7 bacteria, using multiplex real-time PCR. Respiratory disease markers included the Global Asthma Network Questionnaire, the Common-Cold Questionnaire, the Global Initiative for Asthma assessment of asthma control, and the airway resistance at 5 Hz by forced-oscillation technique. Results: The most commonly isolated organisms in both groups (patients and controls) were Streptococcus pneumoniae, Haemophilus influenzae, and rhinovirus. Most patients had multiple isolates (median, 3.5; range, 1–5), which changed during the study period. Types of isolates were 4 bacteria (S. pneumoniae, H. influenzae, Bordetella pertussis, and Bordetella parapertussis) and 6 viruses (rhinovirus, enterovirus, metapneumovirus, adenovirus, coronaviruses, and parainfluenza viruses). Similar isolates, including influenza A-H3 virus and bocavirus, were detected in the controls. Of the 9 patients with “wheezing disturbing sleep ≥1 per week”, 6 had rhinovirus, 2 coronaviruses, and 1 no detectable viruses. Patients with mild common cold symptoms had significantly higher airway resistance at 5 Hz z-score (P=0.025). Conclusion: Multiple respiratory pathogens were isolated from many patients with asthma, which appeared to contribute to disease symptoms and airway resistance. Minimizing children’s exposure to respiratory pathogens might be beneficial, especially during winter. Keywords: asthma, inhaled corticosteroids, respiratory pathogens, nasopharyngeal colonization, communicable diseases Date A point or period of time associated with an event in the lifecycle of the resource 2018 Subject The topic of the resource Asthma, inhaled corticosteroids, respiratory pathogens, nasopharyngeal colonization, Communicable diseases Identifier An unambiguous reference to the resource within a given context DOI: Source A related resource from which the described resource is derived Journal of Asthma and Allergy Publisher An entity responsible for making the resource available Dove Medical Press Coverage The spatial or temporal topic of the resource, the spatial applicability of the resource, or the jurisdiction under which the resource is relevant Immunologic diseases. Allergy Language A language of the resource EN