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A single-center, retrospective study of COVID-19 features in children: a descriptive investigation
Abstract Background Compared to adults, there are relatively few studies on COVID-19 infection in children, and even less focusing on the unique features of COVID-19 in children in terms of laboratory findings, locations of computerized tomography…
Position: 9932 (26 views)
A Single-Center Experience with Lung Transplants During the COVID-19 Pandemic.
BACKGROUND This single-center study analyzed distinctions between lung transplants performed in the Department of Cardiac and Vascular surgery of the University Clinical Center in Gdańsk, Poland before and during the COVID-19 pandemic. MATERIAL AND…
Position: 19338 (15 views)
A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2.
The SARS-CoV-2 pandemic has caused over 1 million deaths globally, mostly due to acute lung injury and acute respiratory distress syndrome, or direct complications resulting in multiple-organ failures. Little is known about the host tissue immune and…
Position: 16403 (19 views)
A single polar residue and distinct membrane topologies impact the function of the infectious bronchitis coronavirus E protein.
The coronavirus E protein is a small membrane protein with a single predicted hydrophobic domain (HD), and has a poorly defined role in infection. The E protein is thought to promote virion assembly, which occurs in the Golgi region of infected…
Position: 12559 (23 views)
A single dose of recombinant VSV-∆G-spike vaccine provides protection against SARS-CoV-2 challenge
Here, the authors generate a replication-competent VSV based vaccine expressing SARS-CoV-2 spike protein and show protection in the hamster model with one dose. Analysis of the antibody response in mice shows induction of neutralizing antibodies and…
Position: 14523 (21 views)
A Simulation on Potential Secondary Spread of Novel Coronavirus in an Exported Country Using a Stochastic Epidemic SEIR Model
Ongoing outbreak of pneumonia caused by novel coronavirus (2019-nCoV) began in December 2019 in Wuhan, China, and the number of new patients continues to increase. Even though it began to spread to many other parts of the world, such as other Asian…
Position: 13535 (22 views)
A Simulation of a COVID-19 Epidemic Based on a Deterministic SEIR Model
An epidemic disease caused by a new coronavirus has spread in Northern Italy with a strong contagion rate. We implement an SEIR model to compute the infected population and the number of casualties of this epidemic. The example may ideally regard the…
Position: 5487 (34 views)
A simulation modelling toolkit for organising outpatient dialysis services during the COVID-19 pandemic.
This study presents two simulation modelling tools to support the organisation of networks of dialysis services during the COVID-19 pandemic. These tools were developed to support renal services in the South of England (the Wessex region caring for…
Position: 18776 (16 views)
A simple, reproducible and accurate lung ultrasound technique for COVID-19: when less is more.
Position: 10737 (25 views)
A simple tool to help ruling-out Covid-19 in the emergency department: derivation and validation of the LDH-CRP-Lymphocyte (LCL) score
After the outbreak of the Covid-19 pandemic, cases of SARSCoV- 2 infections may gradually decrease in the next months. Given the reduced prevalence of the disease, Emergency Departments (ED) are starting to receive more and more non- Covid19…
Position: 9171 (27 views)