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Polyclonal preparation of IgM as an adjuvant therapy has been reported as a relevant immunomodulant therapy in several infectious diseases, exhibiting, in most cases, improvement of the clinical course. No drug has demonstrated therapeutic efficacy…

Background: The discovery of the coronavirus disease 2019 (COVID-19) during a pneumonia outbreak in Wuhan city (China) has raised a global public health concern, as the city consists of around 11 million people and is considered a major transport and…

Background: As we live in an interconnected globalized world, people and the diseases they carry can be easily transmitted to any place in a matter of hours. SARS-CoV-2 began like all new viruses with an ordinary moment when a cluster of patients…

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that is responsible for the 2019–2020 pandemic. In this comprehensive review, we discuss the current published literature surrounding the SARS-CoV-2 virus. We examine…

SARS CoV appeared in 2003 in China, transmitted from bats to humans via eating infected animals. It affected 8,096 humans with a death rate of 11% affecting 21 countries. The receptor binding domain (RBD) in S protein of this virus gets attached with…

Specific highly affinity recognition of imports is crucial for the viral proteins nuclear localization. One of the drugs that affects the viral nuclear localization signal is ivermectin. It is shown that the addition of 5 mcM ivermectin to Vero-hSLAM…

Kerala, a state with high development indices distinguished with its Kerala Model of Development (UN, 1975), is also affected by recent Pandemic COVID'19 as other states and nations worldwide.  The existing socio-economic analysis of the State…

Restricted movement and preventive actions have been introduced to break the chain of transmission of a new coronavirus. This study was conducted to determine the level of knowledge, awareness, attitude and preventive behaviour regarding the…

In Madagascar, despite an influenza surveillance established since 1978, little is known about the etiology and prevalence of viruses other than influenza causing influenza-like illnesses (ILIs).From July 2008 to June 2009, we collected respiratory…

Corona Virus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome coronavirus (SARS CoV-2) has been declared a worldwide pandemic by WHO recently. The complete understanding of the complex genomic structure of SARS CoV-2 has enabled…